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Investors: Will a Psychedelic Drug Take This Pharma Stock to the Next Level?

February 8, 2022 ( Newswire) Algernon Pharmaceuticals plans to be the world’s first company to test the psychedelic drug DMT in stroke patients, and it’s close to achieving its goal.

Algernon Pharmaceuticals Inc. (AGN:CSE; AGNPF:OTCQB; AGW:FSE), a Canadian publicly traded drug development company that recently applied to up-list on the Nasdaq, announced that it plans to be the world’s first company to test the psychedelic drug DMT in stroke patients, and it’s close to achieving its goal.

With a Phase 1 DMT clinical study planned to start before the end of March 2022 to test a new IV formulation of N,N-dimethyltryptamine (DMT), and a Phase 2 acute stroke study planned to begin before the end of the year, the company said it is far ahead of others thinking about psychedelic drug stroke research.

“It is clear from the early preclinical data that DMT encourages neurons to grow and make new connections called neuroplasticity,” said Algernon Chief Executive Officer Christopher Moreau. “The strong preclinical data has motivated me to see if DMT will help treat people that have suffered a stroke.”

Dr. Rick Strassman, who conducted early research on DMT in the 1990s and wrote a book called “DMT: The Spirit Molecule,” said he has yet to see preclinical data on any other drug that appears more promising as a possible treatment for stroke patients than DMT.

“When I did my research on DMT, I was focused on its psychoactive properties,” he said. “But it is clearly showing in the preclinical research that it appears to also have structural and functional roles in helping the brain heal from ischemic injury.”

Strassman, along with other global experts on psychedelic drugs, stroke care physicians, and stroke research specialists have signed on to help Algernon as consultants to guide the company as it moves into human trials. Strassman, Moreau, and consultant Dr. David Nutt appeared on Streetwise Live! on Jan. 27, 2022 to discuss the promise of DMT.

Here’s why this is important

Each year, there are approximately 15 million strokes globally, with nearly 800,000 occurring in the U.S. alone, according to the Centers for Disease Control and Prevention. Approximately 87% of all strokes are ischemic strokes, which occur when a blood clot blocks blood flow to the brain causing brain neurons to die.

Currently, medication treatment for an ischemic stroke is limited to a clot buster called a Tissue Plasminogen Activator (“TPA”), or simple blood thinners. Patients being treated with a TPA must receive the drug within three to 4.5 hours of the stroke injury (the treatment window). For this reason, only about 2% to 10% of stroke patients receive TPA on a global average, according to a journal article published by the American Heart Association.

But for most stroke patients, the current standard of care is having your vitals stabilized (blood pressure, oxygenation, blood glucose, heart rate, and hydration) and to hope and pray for the best. “One can truly say that despite all our medical advances, in the year 2022, there is very little for the vast majority of stroke patients accept hope and prayer and to me that’s not good enough, we need effective treatments as well,” Moreau said.

Enter DMT, a known psychedelic compound. DMT occurs naturally in many plant species and animals – including humans – and has been used in religious ceremonies as a traditional spiritual medicine by indigenous people in the Amazonian basin in a drink called ayahuasca.

Several preclinical stroke studies have demonstrated that DMT helps reduce brain tissue damage and promote neurogenesis (growth of new neurons) as well as structural and functional neural recovery (plasticity), the company said. These are key processes involved in the brain’s ability to form neurons and reorganize synaptic connections, which are needed for healing following a brain injury.

With many hundreds of stroke treatment agents having failed in drug development pathways over the past 40 years, Moreau said DMT, the spirit molecule, may be just what the doctor ordered to help save your life.

Independent investor PennyQueen said Algernon’s practice of repurposing drugs that have already been approved for one indication to use with another condition is a reason it’s one of only two pharmaceutical stocks in her portfolio.

“Biotech is always risky, but Algernon has found ways to make the process faster and remove a significant part of the overall risk,” she wrote. “Combine this with multiple other drug candidates in their pipeline, total addressable markets in the billions, and you have the potential for a winner of staggering proportions.”

Algernon can generally skip the first phase of trials for a repurposed drug because of its established safety history, said Steven Palmer, chief information officer and president of AlphaNorth Asset Management, one of Canada’s top-rated hedge funds.

“They already know that the drug is safe, and they can get right into the Phase 2, to identify whether it works or not,” Palmer said.

Bob Moriarty, founder of, said in January that he believes the company has a lot of “potential.”

“The company has a lot of good things in the works, and there should be a constant flow of news,” Moriarty said. “It’s the kind of company that could be a $500 million market cap in a takeout after success in any one of several drug trials.”


1) Steve Sobek compiled this article for Streetwise Reports LLC. He or members of his household own securities of the following companies mentioned in the article: None. He and members of his household are paid by the following companies mentioned in this article: None. His company has a financial relationship with the following companies referred to in this article: None.

2) The following companies mentioned in this article are billboard sponsors of Streetwise Reports: Algernon Pharmaceuticals Inc. Click here for important disclosures about sponsor fees. An affiliate of Streetwise Reports is conducting a digital media marketing campaign for this article on behalf of Algernon Pharmaceuticals Inc. Please click here for more information.

3) Comments and opinions expressed are those of the specific experts and not of Streetwise Reports or its officers. The information provided above is for informational purposes only and is not a recommendation to buy or sell any security.

4) The article does not constitute investment advice. Each reader is encouraged to consult with his or her individual financial professional and any action a reader takes as a result of information presented here is his or her own responsibility. By opening this page, each reader accepts and agrees to Streetwise Reports’ terms of use and full legal disclaimer. This article is not a solicitation for investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company mentioned on Streetwise Reports.

5) From time to time, Streetwise Reports LLC and its directors, officers, employees or members of their families, as well as persons interviewed for articles and interviews on the site, may have a long or short position in securities mentioned. Directors, officers, employees or members of their immediate families are prohibited from making purchases and/or sales of those securities in the open market or otherwise from the time of the decision to publish an article until three business days after the publication of the article. The foregoing prohibition does not apply to articles that in substance only restate previously published company releases. As of the date of this article, officers and/or employees of Streetwise Reports LLC (including members of their household) own securities of Algernon Pharmaceuticals Inc., a company mentioned in this article.

6) This article does not constitute medical advice. Officers, employees and contributors to Streetwise Reports are not licensed medical professionals. Readers should always contact their healthcare professionals for medical advice.

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